| Level | Ability | Skill | Mana | Range | School | Cost |
|---|
|
| 60 |  | Deadly Poison V (Rank 5) | | 100 yd range | | Instant | | Target takes 23 Nature damage every 3 seconds. |
| Deadly Poison V | | Rank 5 | |
| | | 100 yds | Nature | |
| 60 | | Deadly Poison V (Rank 5) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 30% chance of poisoning the enemy for 92 Nature damage over 12 sec. Stacks up to 5 times on a single target. 180 charges. |
| Deadly Poison V | | Rank 5 | |
| | | | Physical | |
| 60 | | Deadly Poison V (Rank 5) | | 100 yd range | | Instant | | Target takes 34 Nature damage every 3 seconds. |
| Deadly Poison V | | Rank 5 | |
| | | 100 yds | Nature | |
| | | | 40 yds | Physical | |
| | | | 40 yds | Physical | |
| 51 | | | | | Nature | |
| 1 |  | Engrave Belt - Poisoned Knife | | 3 sec cast | Engrave your belt with the Poisoned Knife rune:
Instantly throw your off-hand weapon to deal normal off-hand weapon damage with a 100% chance to apply the poison from your off-hand weapon to the target. Awards 1 combo point. Refunds 5 Energy per application of Deadly Poison on the target.
Poisoned Knife benefits from all talents and effects that trigger from or modify Sinister Strike. |
| Engrave Belt - Poisoned Knife | | | |
| | | | Physical | |
| 20 |  | Fast Acting Poison (Rank 1) | | Melee Range | | Instant | | A fast acting poison that does 19 to 31 damage to the target. |
| Fast Acting Poison | | Rank 1 | |
| | | Melee Range | Nature | |
| | Improved Poisons | | Increases the chance to apply Poisons to your target by 10%, and gives Poison applications a 50% chance to not consume a charge. |
| Improved Poisons | | | |
| | | | Physical | |
| | Improved Poisons | | Increases the chance to apply poisons to your target by 5%. |
| Improved Poisons | | | |
| | | | Physical | |
| 20 | | Instant Poison (Rank 1) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 13 to 17 Nature damage. 60 charges. |
| Instant Poison | | Rank 1 | |
| | | | Physical | |
| 20 | | Instant Poison (Rank 1) | | 100 yd range | | Instant | | 13 to 17 Nature damage. |
| Instant Poison | | Rank 1 | |
| | | 100 yds | Nature | |
| 20 | | Instant Poison (Rank 1) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 13 to 17 Nature damage. 60 charges. |
| Instant Poison | | Rank 1 | |
| | | | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
| 20 | | | | 10 yds | Nature | |
| 28 | | Instant Poison II (Rank 2) | | 100 yd range | | Instant | | 20 to 26 Nature damage. |
| Instant Poison II | | Rank 2 | |
| | | 100 yds | Nature | |
| 28 | | Instant Poison II (Rank 2) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 20 to 26 Nature damage. 85 charges. |
| Instant Poison II | | Rank 2 | |
| | | | Physical | |
| 28 | | Instant Poison II (Rank 2) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 20 to 26 Nature damage. 85 charges. |
| Instant Poison II | | Rank 2 | |
| | | | Physical | |
| 36 | | Instant Poison III (Rank 3) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 29 to 37 Nature damage. 105 charges. |
| Instant Poison III | | Rank 3 | |
| | | | Physical | |
| 36 | | Instant Poison III (Rank 3) | | 100 yd range | | Instant | | 29 to 37 Nature damage. |
| Instant Poison III | | Rank 3 | |
| | | 100 yds | Nature | |
| 36 | | Instant Poison III (Rank 3) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 29 to 37 Nature damage. 105 charges. |
| Instant Poison III | | Rank 3 | |
| | | | Physical | |
| 44 | | Instant Poison IV (Rank 4) | | 100 yd range | | Instant | | 45 to 57 Nature damage. |
| Instant Poison IV | | Rank 4 | |
| | | 100 yds | Nature | |
| 44 | | Instant Poison IV (Rank 4) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 45 to 57 Nature damage. 130 charges. |
| Instant Poison IV | | Rank 4 | |
| | | | Physical | |
| 44 | | Instant Poison IV (Rank 4) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 45 to 57 Nature damage. 1800 charges. |
| Instant Poison IV | | Rank 4 | |
| | | | Physical | |
| 1 | | | | | Physical | |
| 52 | | Instant Poison V (Rank 5) | | 100 yd range | | Instant | | 62 to 80 Nature damage. |
| Instant Poison V | | Rank 5 | |
| | | 100 yds | Nature | |
| 52 | | Instant Poison V (Rank 5) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 62 to 80 Nature damage. 150 charges. |
| Instant Poison V | | Rank 5 | |
| | | | Physical | |
| 52 | | Instant Poison V (Rank 5) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 62 to 80 Nature damage. 150 charges. |
| Instant Poison V | | Rank 5 | |
| | | | Physical | |
| 60 | | Instant Poison VI (Rank 6) | | 100 yd range | | Instant | | 76 to 100 Nature damage. |
| Instant Poison VI | | Rank 6 | |
| | | 100 yds | Nature | |
| 60 | | Instant Poison VI (Rank 6) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 76 to 100 Nature damage. 175 charges. |
| Instant Poison VI | | Rank 6 | |
| | | | Physical | |
| 60 | | Instant Poison VI (Rank 6) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy which instantly inflicts 76 to 100 Nature damage. 175 charges. |
| Instant Poison VI | | Rank 6 | |
| | | | Physical | |
| 21 |  | Leech Poison | | Melee Range | | Instant | | Drains 15 health from an enemy every 5 sec. over 40 sec., transferring it to the caster. |
| Leech Poison | | | |
| | | Melee Range | Nature | |
| 1 | | Leech Poison | | Melee Range | | Instant | | Drains 120 health from an enemy every 5 sec. over 45 sec., transferring it to the caster. |
| Leech Poison | | | |
| | | Melee Range | Nature | |
| | Leech Poison | | 20 yd range | | Instant | | Drains 2 health from an enemy every 2 sec. over 16 sec., transferring it to the caster. |
| Leech Poison | | | |
| | | 20 yds | Nature | |
|  | Lethargic Poison | | 0.5 sec cast | | The caster spits a lethargic poison at players, inflicting 300 Nature damage every 3 sec for 15 sec. This poison reduces hit chance by 50% and increases ability costs by 100%. |
| Lethargic Poison | | | |
| | | | Nature | |
| | Lethargic Poison | | 2.5 sec cast | | The caster spits a lethargic poison at players, inflicting 100 Nature damage every 3 sec for 15 sec. This poison reduces hit chance by 50% and increases ability costs by 100%. |
| Lethargic Poison | | | |
| | | | Nature | |
| 24 | | | | 100 yds | Nature | |
| 24 |  | Mind-numbing Poison (Rank 1) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 40% for 10 sec. 75 charges. |
| Mind-numbing Poison | | Rank 1 | |
| | | | Physical | |
| 24 | | Mind-numbing Poison (Rank 1) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 40% for 10 sec. 75 charges. |
| Mind-numbing Poison | | Rank 1 | |
| | | | Physical | |
| 38 | | | | 40 yds | Nature | |
| 38 | | | | 100 yds | Nature | |
| 38 | | Mind-numbing Poison II (Rank 2) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 50% for 12 sec. 115 charges. |
| Mind-numbing Poison II | | Rank 2 | |
| | | | Physical | |
| 38 | | Mind-numbing Poison II (Rank 2) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 50% for 12 sec. 115 charges. |
| Mind-numbing Poison II | | Rank 2 | |
| | | | Physical | |
| 52 | | | | 100 yds | Nature | |
| 52 | | Mind-numbing Poison III (Rank 3) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 60% for 14 sec. 150 charges. |
| Mind-numbing Poison III | | Rank 3 | |
| | | | Physical | |
| 52 | | Mind-numbing Poison III (Rank 3) | | 3 sec cast | Coats a weapon with poison that lasts for 30 minutes.
Each strike has a 20% chance of poisoning the enemy, increasing their casting time by 60% for 14 sec. 150 charges. |
| Mind-numbing Poison III | | Rank 3 | |
| | | | Physical | |
| | | | Melee Range | Nature | |
| | | | Melee Range | Nature | |
| | | | 100 yds | Nature | |
