| Level | Ability | Skill | Mana | Range | School | Cost |
|---|
|
|  | Plague | | 50000 yd range | | Instant |
| Plague | | | |
| | | 50000 yds | Nature | |
|  | Plague | | 50000 yd range | | Instant |
| Plague | | | |
| | | 50000 yds | Nature | |
| | | | | Physical | |
| 62 | | | | | Physical | |
| 17 |  | Plague Cloud | | 30 yd range | | 2 sec cast | 7 min cooldown | | Reduces Strength by 14, Agility by 14, and Intellect by 14 for all enemies in a selected area for 4 min. |
| Plague Cloud | | | |
| | | 30 yds | Shadow | |
| 17 | | | | 30 yds | Shadow | |
| 20 | | | | 30 yds | Nature | |
| 1 |  | Plague Cloud | | 2.5 sec cast | | Reduces Strength by 60, Agility by 60, and Intellect by 60 for all enemies in a selected area for 4 min. |
| Plague Cloud | | | |
| | | | Shadow | |
| | | | 100 yds | Nature | |
| | | | 100 yds | Nature | |
| | | | | Physical | |
|  | Plague Doctor's Laboratory (Tier 3) | | 1 yd range | | 10 sec cast | 1 hour cooldown | Places a Plague Doctor's Laboratory that contains healing potions, poultices, and provides all of the benefits of a First Aid Kit. Requires a Campfire nearby.
May be placed over a First Aid Kit to replace it. All camping features share a cooldown of 1 hour. |
| Plague Doctor's Laboratory | | Tier 3 | |
| | | 1 yds | Physical | |
| 20 | | | | | Nature | |
| 20 | | | | | Nature | |
| 28 |  | Plague Mind | | 30 yd range | | 4 sec cast | | Diseases an enemy for 10 min., draining 21 mana every 10 sec. and transferring it to the caster. |
| Plague Mind | | | |
| | | 30 yds | Shadow | |
| 28 |  | Plague Mind | | 30 yd range | | 4 sec cast | | Diseases an enemy for 10 min., draining 21 mana every 10 sec. and transferring it to the caster. |
| Plague Mind | | | |
| | | 30 yds | Shadow | |
| 1 | | | | | Nature | |
| 20 |  | Plague Nova | | Instant | | Inflicts Nature damage to nearby enemies, slowing them for up to 8 sec. |
| Plague Nova | | | |
| | | | Nature | |
| | | | | Physical | |
| | | | | Physical | |
| | | | | Physical | |
| | | | | Physical | |
| | | | 100 yds | Physical | |
| | | | 50000 yds | Physical | |
| | | | 50000 yds | Physical | |
| | | | 50000 yds | Physical | |
| | | | 50000 yds | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
| | | | 100 yds | Physical | |
|  | Plaguebloom | | 100 yd range | | Instant | | Collecting herbs. |
| Plaguebloom | | | |
| | | 100 yds | Physical | |
| 20 |  | Plagued Shot | | 8-40 yd range | | 3 sec cast | | Dazes an enemy. |
| Plagued Shot | | | |
| | | 8-40 yds | Nature, Shadow | |
|  | Plagueheart | | Your spell critical hits generate 25% less threat. In addition, Corruption, Immolate, Curse of Agony, and Siphon Life generate 25% less threat. |
| Plagueheart | | | |
| | | | Physical | |
|  | Plagues Deck | | 3 sec cast | | Combine the Ace through Eight of Plagues to complete the set. |
| Plagues Deck | | | |
| | | | Physical | |
|  | Blood Plague | | 20 yd range | | Instant | 1 min cooldown | | Inflict Blood Plague upon the enemy target which deals 120 Shadow damage every 3 sec for 15 sec. |
| Blood Plague | | | |
| | | 20 yds | Shadow | |
| | | | | Physical | |
| 22 | | | | 10 yds | Shadow | |
| | | | | Nature | |
| 8 |  | Curse of the Plague Rat | | 10% of base mana | 30 yd range | | 1.5 sec cast | | Transforms an enemy into a rat, forcing it to wander around and deal 500 Nature damage every 2 sec to nearby allies for up to 14 sec. While wandering, the rat cannot attack or cast spells, but regenerates very quickly. Only one target can be cursed at a time. |
| Curse of the Plague Rat | | | |
| | 10% of base mana | 30 yds | Shadow | |
|  | Curse of the Plaguebringer | | Instant | | Curses the target with the Curse of the Plaguebringer. If the target is not dispelled of the curse, the target will become infected along with all nearby allies in a selected area with the Wrath of the Plaguebringer. |
| Curse of the Plaguebringer | | | |
| | | | Shadow | |
| 30 | | | | | Nature | |
| 25 |  | Dark Plague | | 30 yd range | | Instant | | Inflicts 565 Nature damage to an enemy, then an additional 39 damage every 5 sec. for 90 sec. |
| Dark Plague | | | |
| | | 30 yds | Nature | |
| 25 |  | Dark Plague | | 30 yd range | | Instant | | Inflicts 320 Nature damage to an enemy, then an additional 39 damage every 5 sec. for 90 sec. |
| Dark Plague | | | |
| | | 30 yds | Nature | |
| 20 |  | Devouring Plague (Rank 1) | | 215 Mana | 30 yd range | | Instant | 1 min cooldown | Afflicts the target with a disease that causes 128 Shadow damage over 24 sec. Damage caused by the Devouring Plague heals the caster.
Periodic damage can critically strike. |
| Devouring Plague | | Rank 1 | |
| | 215 | 30 yds | Shadow | |
| 28 |  | Devouring Plague (Rank 2) | | 350 Mana | 30 yd range | | Instant | 1 min cooldown | Afflicts the target with a disease that causes 232 Shadow damage over 24 sec. Damage caused by the Devouring Plague heals the caster.
Periodic damage can critically strike. |
| Devouring Plague | | Rank 2 | |
| | 350 | 30 yds | Shadow | |
| 36 |  | Devouring Plague (Rank 3) | | 495 Mana | 30 yd range | | Instant | 1 min cooldown | Afflicts the target with a disease that causes 344 Shadow damage over 24 sec. Damage caused by the Devouring Plague heals the caster.
Periodic damage can critically strike. |
| Devouring Plague | | Rank 3 | |
| | 495 | 30 yds | Shadow | |
| 44 |  | Devouring Plague (Rank 4) | | 645 Mana | 30 yd range | | Instant | 1 min cooldown | Afflicts the target with a disease that causes 488 Shadow damage over 24 sec. Damage caused by the Devouring Plague heals the caster.
Periodic damage can critically strike. |
| Devouring Plague | | Rank 4 | |
| | 645 | 30 yds | Shadow | |